I'm buying a Lexus is300 soon with 76,600 miles on it in excellent condition (I didn't spot a ding ANYWHERE nor any problems, also had an expert mechanic that is a friend of mines check it). I am planning to own and drive the car around for a while, like the next 7-10 years, and I wanted to know if anyone has had any problems with an is300 with 100,000 miles or over on the engine. An expert car mechanic told me "Toyota's are on demand, they will run for a while, maybe at 300,000 miles until you will start seeing problems." The current car I drive, a 1998 Toyota Avalon, has 136,800 miles on it and NEVER in my life had a problem with that car, EVER. I also have a friend who owns a 1991 Acura Integra with a whopping 317,000 miles on it, the technicals all stock and it still runs great, minor problems with head gasket and fuses. If anyone did, please state what was the problem and at how many miles, also year of veichle. I would gladly appreciate it, thanks so much IS community. Enjoy.